Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
- Primary Antibodies ›
- RBPJ Antibodies
Proteintech
View all (12) RBPJ antibodies
Cite RBPJ Polyclonal Antibody
FIGURE: 1 / 3
{{ $ctrl.currentElement.advancedVerification.fullName }}
{{ $ctrl.currentElement.advancedVerification.text }}
RBPJ Antibody (30044-1-AP) in IHC (P)
Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 30044-1-AP (RBPJ antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
Published figure supplied by
{{$ctrl.videoDesc}}
{{$ctrl.videoLongDesc}}
Product Details
30044-1-AP
Applications
Tested Dilution
Publications
Western Blot(WB)
1:500-1:2,000
-
Immunohistochemistry (Paraffin) (IHC (P))
1:50-1:500
-
ELISA(ELISA)
Assay-dependent
-
Immunoprecipitation(IP)
0.5-4 µg/1-3 mg of protein lysate
-
Product Specifications
Species Reactivity
Human,Mouse
Host/Isotype
Rabbit/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein
Conjugate
Unconjugated
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MYRCGESMLC VVPDISAFRE GWRWVRQPVQ VPVTLVRNDG IIYSTSLTFT YTPEPGPRPH CSAAGAILRA NSSQVPPNES NTNSEGSYTN ASTNSTSVTS STATVVS
Target Information
CSL plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair. The protein is abundantly expressed in heart and skeletal muscle and expression is increased by passive stretch. Mutations in this gene can lead to X-linked deafness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product
Bioinformatics
Protein Aliases:CBF-1; H-2K binding factor-2; immunoglobulin kappa J region recombination signal binding protein 1; J kappa-recombination signal-binding protein; RBP-J; RBP-J kappa; RBP-JK; rbp-jkappa; Recombining binding protein suppressor of hairless; Renal carcinoma antigen NY-REN-30; suppressor of hairless hom*olog
Gene Aliases:AI843960; AOS3; CBF1; csl; IGKJRB; IGKJRB1; Igkrsbp; KBF2; RBP-J; RBP-J kappa; RBPJ; RBPJK; RBPSUH; SUH
UniProt ID:(Human) Q06330, (Mouse) P31266
Entrez Gene ID:(Human) 3516, (Mouse) 19664
Molecular Function: DNA-binding transcription factor
Function(s)
negative regulation of transcription from RNA polymerase II promoterangiogenesissomitogenesisepithelial to mesenchymal transitionblood vessel remodelinginflammatory response to antigenic stimulussecondary heart field specificationoutflow tract morphogenesisendocardium morphogenesisepithelial to mesenchymal transition involved in endocardial cushion formationcardiac left ventricle morphogenesisventricular trabecula myocardium morphogenesisregulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiationDNA recombinationtranscription initiation from RNA polymerase II promoterhumoral immune responseNotch signaling pathwaypositive regulation of transcription of Notch receptor targetnegative regulation of cell proliferationauditory receptor cell fate commitmentepidermal cell fate specificationpituitary gland developmentB cell differentiationkeratinocyte differentiationnegative regulation of ossificationpositive regulation of BMP signaling pathwaysomatic stem cell population maintenancedorsal aorta morphogenesisatrioventricular canal developmentdefense response to bacteriummyeloid dendritic cell differentiationnegative regulation of cell differentiationnegative regulation of transcription, DNA-templatedpositive regulation of transcription from RNA polymerase II promoterregulation of timing of cell differentiationsebaceous gland developmenthair follicle maturationpositive regulation of cardiac muscle cell proliferationClara cell differentiationlabyrinthine layer blood vessel developmentarterial endothelial cell fate commitmentNotch signaling involved in heart developmentpositive regulation of transcription from RNA polymerase II promoter in response to hypoxiablood vessel lumenizationinterleukin-4 secretionblood vessel endothelial cell fate specificationpositive regulation of ERBB signaling pathwaypositive regulation of ephrin receptor signaling pathwaypositive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitmentpositive regulation of cell proliferation involved in heart morphogenesisheart loopingendocardium developmenttranscription, DNA-templatedregulation of transcription, DNA-templatedregulation of transcription from RNA polymerase II promotertranscription from RNA polymerase II promoterheart developmentpositive regulation of cell proliferationregulation of gene expressionpositive regulation of gene expressionnegative regulation of neuron projection developmentnegative regulation of smooth muscle cell migrationhemopoiesisneuron differentiationnegative regulation of smooth muscle cell apoptotic processpositive regulation of Notch signaling pathway involved in heart inductioncell fate commitmentpositive regulation of transcription, DNA-templatedpositive regulation of smooth muscle cell proliferationartery morphogenesisNotch signaling pathway involved in arterial endothelial cell fate commitmentregulation of cell adhesion involved in heart morphogenesisdetermination of heart left/right asymmetry
Process(es)
recombinase activityRNA polymerase II core promoter proximal region sequence-specific DNA bindingRNA polymerase II core promoter sequence-specific DNA bindingtranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingRNA polymerase II repressing transcription factor bindingDNA bindingchromatin bindingtranscription factor activity, sequence-specific DNA bindingprotein bindingtranscription factor bindingsequence-specific DNA bindingprotein N-terminus bindingtranscription factor activity, RNA polymerase II core promoter proximal region sequence-specific bindingtranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingprotein complex binding
It has to be done as per old AB suggested Products section.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support