RBPJ Polyclonal Antibody (30044-1-AP) (2024)

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RBPJ Polyclonal Antibody (30044-1-AP) (1)

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  • Primary Antibodies
  • RBPJ Antibodies

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Protocols

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RBPJ Polyclonal Antibody (30044-1-AP) (2)

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RBPJ Polyclonal Antibody (30044-1-AP) (3)

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RBPJ Antibody (30044-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 30044-1-AP (RBPJ antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more

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RBPJ Polyclonal Antibody (30044-1-AP) (4)

RBPJ Polyclonal Antibody (30044-1-AP) (5)

RBPJ Polyclonal Antibody (30044-1-AP) (6)

Product Details

30044-1-AP

Applications

Tested Dilution

Publications

Western Blot(WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

-

ELISA(ELISA)

Assay-dependent

-

Immunoprecipitation(IP)

0.5-4 µg/1-3 mg of protein lysate

-

Product Specifications

Species Reactivity

Human,Mouse

Host/Isotype

Rabbit/ IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein

Conjugate

Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Immunogen sequence: MYRCGESMLC VVPDISAFRE GWRWVRQPVQ VPVTLVRNDG IIYSTSLTFT YTPEPGPRPH CSAAGAILRA NSSQVPPNES NTNSEGSYTN ASTNSTSVTS STATVVS

Target Information

CSL plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair. The protein is abundantly expressed in heart and skeletal muscle and expression is increased by passive stretch. Mutations in this gene can lead to X-linked deafness.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases:CBF-1; H-2K binding factor-2; immunoglobulin kappa J region recombination signal binding protein 1; J kappa-recombination signal-binding protein; RBP-J; RBP-J kappa; RBP-JK; rbp-jkappa; Recombining binding protein suppressor of hairless; Renal carcinoma antigen NY-REN-30; suppressor of hairless hom*olog

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Gene Aliases:AI843960; AOS3; CBF1; csl; IGKJRB; IGKJRB1; Igkrsbp; KBF2; RBP-J; RBP-J kappa; RBPJ; RBPJK; RBPSUH; SUH

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Molecular Function: RBPJ Polyclonal Antibody (30044-1-AP) (7)DNA-binding transcription factor

Function(s)

negative regulation of transcription from RNA polymerase II promoterangiogenesissomitogenesisepithelial to mesenchymal transitionblood vessel remodelinginflammatory response to antigenic stimulussecondary heart field specificationoutflow tract morphogenesisendocardium morphogenesisepithelial to mesenchymal transition involved in endocardial cushion formationcardiac left ventricle morphogenesisventricular trabecula myocardium morphogenesisregulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiationDNA recombinationtranscription initiation from RNA polymerase II promoterhumoral immune responseNotch signaling pathwaypositive regulation of transcription of Notch receptor targetnegative regulation of cell proliferationauditory receptor cell fate commitmentepidermal cell fate specificationpituitary gland developmentB cell differentiationkeratinocyte differentiationnegative regulation of ossificationpositive regulation of BMP signaling pathwaysomatic stem cell population maintenancedorsal aorta morphogenesisatrioventricular canal developmentdefense response to bacteriummyeloid dendritic cell differentiationnegative regulation of cell differentiationnegative regulation of transcription, DNA-templatedpositive regulation of transcription from RNA polymerase II promoterregulation of timing of cell differentiationsebaceous gland developmenthair follicle maturationpositive regulation of cardiac muscle cell proliferationClara cell differentiationlabyrinthine layer blood vessel developmentarterial endothelial cell fate commitmentNotch signaling involved in heart developmentpositive regulation of transcription from RNA polymerase II promoter in response to hypoxiablood vessel lumenizationinterleukin-4 secretionblood vessel endothelial cell fate specificationpositive regulation of ERBB signaling pathwaypositive regulation of ephrin receptor signaling pathwaypositive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitmentpositive regulation of cell proliferation involved in heart morphogenesisheart loopingendocardium developmenttranscription, DNA-templatedregulation of transcription, DNA-templatedregulation of transcription from RNA polymerase II promotertranscription from RNA polymerase II promoterheart developmentpositive regulation of cell proliferationregulation of gene expressionpositive regulation of gene expressionnegative regulation of neuron projection developmentnegative regulation of smooth muscle cell migrationhemopoiesisneuron differentiationnegative regulation of smooth muscle cell apoptotic processpositive regulation of Notch signaling pathway involved in heart inductioncell fate commitmentpositive regulation of transcription, DNA-templatedpositive regulation of smooth muscle cell proliferationartery morphogenesisNotch signaling pathway involved in arterial endothelial cell fate commitmentregulation of cell adhesion involved in heart morphogenesisdetermination of heart left/right asymmetry

Process(es)

recombinase activityRNA polymerase II core promoter proximal region sequence-specific DNA bindingRNA polymerase II core promoter sequence-specific DNA bindingtranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingRNA polymerase II repressing transcription factor bindingDNA bindingchromatin bindingtranscription factor activity, sequence-specific DNA bindingprotein bindingtranscription factor bindingsequence-specific DNA bindingprotein N-terminus bindingtranscription factor activity, RNA polymerase II core promoter proximal region sequence-specific bindingtranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingprotein complex binding

It has to be done as per old AB suggested Products section.

RBPJ Polyclonal Antibody (30044-1-AP) (8)

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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RBPJ Polyclonal Antibody (30044-1-AP) (9)

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RBPJ Polyclonal Antibody (30044-1-AP) (2024)
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