Scientist II, Cell Biology (Upstream/Bioreactor) at Thermo Fisher Scientific | The Muse (2024)

What will you do

Operate and optimize WAVE or Xuri bioreactor systems for cell culture applications.

Design, implement, and troubleshoot experiments involving the culture of various cell lines.

Develop and refine aseptic techniques to ensure contamination-free cell culture.

Perform scale-up study studies to support process development and production.

Maintain detailed and accurate records of experiments, protocols, and results.

Analyze data and present findings to internal teams.

Collaborate with cross-functional teams to support project goals and timelines.

Conduct the preparation of technical reports, manuscripts, and presentations.

Stay current with advancements in bioreactor technology and cell culture methodologies.

Maintain mammalian cell culture including thawing, passaging, expansion, cell banking, and inventory management.

Generate recombinant cell lines including transfection, selection, enrichment, single cell cloning, and clonal expansion.

Characterize cell lines by cell viability analyzer, antigen expression by flow cytometry, cell line identity by molecular typing, and cell line sterility by mycoplasma testing.

Purify antigen or antibody. Perform biochemical and biophysical characterizations including concentration determination, SDS-PAGE, Western Blot, ELISA, and Luminex.

Perform studies or investigations under the mentorship of Cell Biology manager.

Carry out lab duties including preparing buffers, reagents and media, maintaining lab supplies, and supporting other functions in the group.

Give oral presentations at internal meetings.

Perform all activities in compliance with GDP, GMP, regulatory and safety policies.

How will you get here

Education / Experience

B.S or M.S. in Cell Biology, Biotechnology, Bioengineering, Biochemistry, Immunology, Genetics, or a related field in Biological Sciences AND at least 2 years of research/lab experience.

Knowledge, Skills and Abilities

Extensive hands-on experience with WAVE and Xuri bioreactor systems.

Clear understanding of bioreactor, cell culture, cell line development and cell banking principles and practices.

Ability to conduct experiments independently.

Proficiency in aseptic techniques and maintaining sterile environments.

Experience with data analysis software and Microsoft Office.

Strong communication, documentation (organization and record-keeping), and presentation skills.

Ability to perform multi-tasks and balance priorities to meet company goals.

Strong problem-solving skills, identifying root causes, and proposing alternative approaches and feasible solutions.

A complete employee benefits package includes health insurance, life insurance, paid time off (PTO), life insurance, employee stock purchase plan (ESPP), etc.

Compensation and Benefits
The salary range estimated for this position based in California is $73,000.00-$100,000.00.

This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:

• A choice of national medical and dental plans, and a national vision plan, including health incentive programs
• Employee assistance and family support programs, including commuter benefits and tuition reimbursem*nt
• At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
• Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
• Employees' Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards