Anti-BAP1 Antibodies | Invitrogen (2024)

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Antibodies that detect BAP1 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry and Peptide array. These antibodies target BAP1 in Human, Mouse, Rat and Non-human primate samples. Our BAP1 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. Find the BAP1 antibody that fits your needs. Choose from 1 of 28 BAP1 antibodies, which have been validated in experiments with 4 publications and 60 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

BRCA1-associated protein-1, or BAP1, interacts with the RING finger domain of BRCA1. The N-terminal 240 amino acids of the predicted 729-amino acid human protein show hom*ology to ubiquitin C-terminal hydrolases (UCHs), thiol proteases that catalyze proteolytic processing of ubiquitin. In addition, BAP1 contains an acidic region, a highly charged C-terminal region, and 2 putative nuclear localization signals. BAP1 and BRCA1 associate in vivo and have overlapping subnuclear localization patterns. BAP1 enhances BRCA1-mediated inhibition of breast cancer cell growth. Northern blot analysis indicates that BAP1 is expressed as a 4-kb mRNA in all human tissues tested, with A 4. 8-kb transcript expressed exclusively in testis. Northern blot analysis and in situ hybridization reveal that BAP1 and BRCA1 are coexpressed during murine breast development and remodeling. The BAP1 gene has been mapped to 3p21. 3, a region of loss of heterozygosity for breast cancer as well as frequently deleted in lung carcinomas. Intragenic hom*ozygous rearrangements and deletions of BAP1 appear in lung carcinoma cell lines. It has been postulated that BAP1 is a tumor suppressor gene that functions in the BRCA1 growth control pathway.

Synonyms

2300006C11Rik; AA989761; AW553466; BAP1; Brca1 associated protein 1; BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase); BRCA1-associated protein 1; Cerebral protein 6; cerebral protein-13; DKFZp686N04275; FLJ35406; FLJ37180; HUCEP-13; hucep-6; KIAA0272; mKIAA0272; Ubiquitin carboxyl-terminal hydrolase BAP1; ubiquitin C-terminal hydrolase X4; UCHL2; uch-x4

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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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28 results

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28 results

Invitrogen

BAP1 Polyclonal Antibody

Invitrogen

BAP1 Polyclonal Antibody

Target

HumanMouseRat

Details

Rabbit Polyclonal

Application

WB Flow

Price

Online offer:

Cat #PA5-12061

400 µL

Proteintech

BAP1 Polyclonal Antibody

Proteintech

BAP1 Polyclonal Antibody

Target

HumanMouse

Details

Rabbit Polyclonal

Application

WB IHC (P)

Price

Online offer:

Cat #10398-1-AP

150 µL

Invitrogen

BAP1 Monoclonal Antibody (1G8)

Invitrogen

BAP1 Monoclonal Antibody (1G8)

Target

Human

Details

Mouse Monoclonal

Application

WB Flow

Price

Online offer:

Cat #MA1-46087

100 µL

Invitrogen

BAP1 Polyclonal Antibody

Invitrogen

BAP1 Polyclonal Antibody

Target

HumanMouseRat

Details

Rabbit Polyclonal

Application

WB IHC (P) ICC/IF

Price

Online offer:

Cat #PA5-121008

100 µL

Invitrogen

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Anti-BAP1 Antibodies | Invitrogen (2024)

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